Associate Scientist (AZ15522)

Client  is looking for a highly motivated associate scientist with experience in development of molecular assays and expertise in cutting-edge technologies in genomics. The successful candidate will be capable of carrying out studies using various technologies such as whole exome sequencing (WES), RNAseq, qRT-PCR and microarrays to support pre-clinical and clinical studies during various stages of drug discovery and development.
Candidate -
*****direct next generation sequencing experience
- 70 - 80 % time spent in lab
3 + years exp
Requirements

• BS/MS with minimum 3 years of experience in molecular biology
• Minimum 3 years of wet-lab experience developing and implementing assays
• Strong theoretical and practical understanding of nucleic acid analysis
• Extensive experience developing and implementing genotyping and gene expression assays
• Experience in various genomic technologies such as NGS, RNAseq, microarrays and qRT-PCR required
• Experience in working with a variety of analytical platforms and instrumentation
• Some familiarity with drug development process highly desired
• Experience in working independently and collaboratively in a matrixed environment
• Strong written and oral communication skills
• Must be able to interact in a cross functional environment and manage multiple projects simultaneously


Responsibilities

• RNA/DNA purification and characterization from multiple sources (frozen tissue, FFPE tissues, blood, plasma, BMA, sputum, etc.) utilizing various methodologies
• Sample processing for next generation sequencing data generation
• Develop and executing various QC methodologies to assess quality of samples
• Performing WES and RNAseq using multiple NGS technologies
• Developing and executing of qRT-PCR assays on multiple platforms
• Perform microarray experiments as needed to support programs
• Perform analysis of data and summarize results from experiments performed
• Maintain detailed laboratory notes on experiments, generate reports summarizing experimental results and communicate them to project teams.
• Present key results at group meetings and to project teams and stake-holders